Both the video game and television adaptation of The Last of Us end sorely for Ellie and Joel. They're presumably the sole survivors of the massacre at a Firefly hospital where Ellie was determined to die for a Cordyceps vaccine. As the strained surrogate father-daughter duo start a new life in Jackson, Abby Anderson starts a quest for revenge.
Source:https://www.cbr.com/the-last-of-us-kaitlyn-dever-abby-anderson-guide/