ABC's popular medical drama Grey's Anatomy has gained a reputation for regularly shaking up its cast. Some actors left the series — which is approaching 20 seasons on the air — to pursue other opportunities. Others, such as Justin Chambers' Alex Karev, have been written out of the show when those behind the scenes decided it was time to move on from their characters. And then there was Isaiah Washington, who had one of Grey's Anatomy's most controversial exits.
Source：https://www.cbr.com/greys-anatomy-why-isaiah-washington-left/
